DIFFERENTIAL DIAGNOSIS FOR AN ELEVATED aPTT

Heparin Therapy

Sample Contamination with Heparin

Warfarin Therapy

Collection to Test Sample Time Over 4 Hours

Lupus Anticoagulant

Hemophilia

     Factor VIII Deficiency (Hemophilia A)

     Factor IX Deficiency (Hemophilia B, Christmas Disease)

     Factor XI Deficiency

     Factor XII Deficiency (Hageman Factor)

Deficiency of Clotting Factors

     Factor I Deficiency

     Factor II Deficiency

     Factor V Deficiency

von Willebrand Disease

Vitamin K Deficiency

     Dietary

     Antibiotic Therapy

Acute Hepatic Failure

Cirrhosis 

Nephrotic Syndrome

Dysproteinemias

Gauchers Disease

Disseminated Intravascular Coagulation (DIC)

Fibrinolysis

Congenital Afibrogenemia

Ingestion of Rodent Pesticides

     Brodifacoum