MEDICATIONS ASSOCIATED WITH MACROCYTOSIS

Marrow Toxicity

     Alcohol

     Methotrexate

     Mercaptopurine

     Thioguanine

     Azathioprine

     Acyclovir

     Fluorouracil

     Floxuridine

     Azidouridine

     Zidovudine

     Cytosine Arabinoside

     Hydroxyurea

     Cyclophosphamide

     Busulfan

Altered Folate Metabolism

     Oral Contraceptives

     Phenytoin

     Primidone

     Phenobarbital

     Triamterene

     Sulfasalazine

     Sulfamethoxazole

     Trimethoprim

     Pentamidine Isethionate

     Pyrimethamine

     Alcohol

Altered Cobalamin Metabolism

     Cobalamin Malabsorption

     Colchicine

     Neomycin Sulfate

     Para-aminosalicylic Acid

Impaired Cobalamin Utilization

     Nitrous Oxide

Methanol Ingestion