DIFFERENTIAL DIAGNOSIS OF PERIPHERAL NEUROPATHY

Diabetes mellitus

Alcohol

Guillain-Barre syndrome

B12 deficiency

Uremia

Toxins (lead, arsenic)

Medications

     Metronidazole

     Isoniazid

     Vincristine

     Cisplatin

Charcot-Marie-Tooth disease

Hypothyroidism

Infections (syphilis, Lyme disease, HIV)

Amyloidosis

Acromegaly

Porphyria

Systemic lupus erythematosus

Rheumatoid arthritis

Sjogren’s syndrome

Vasculitis

    Wegener's granulomatosis

     Churg-Strauss syndrome 

Sarcoidosis

Ischemic neuropathy

Chronic inflammatory demyelinating polyradiculoneuropathy

Hereditaty neuropathy with predisposition to pressure palsies

Nerve root compression

Peripheral nerve entrapment

Paraneoplastic

Paraproteinemic demyelinating neuropathy

     Monoclonal gammopathy of unknown significance (MGUS)

     Multiple myeloma

     Waldenstrom's macroglobulinemia

     Amyloidosis

     POEMS syndrome (polyneuropathy, organomegaly, endrocinopathy, M protein, and skin changes) 

Globoid cell leukodystrophy

Metachromatic leukodystrophy

Fabry disease

Refsum disease

Cerebrotendinous xanthomatosis

Adrenoleukodystrophy

Adrenomyeloneuropathy

Abetalipoproteinemia

Hypolipoproteinemia